
Biography
Dr. Masako Morishita, Associate Professor in the Department of Family Medicine, is an environmental exposure science/population health researcher. Dr. Morishita's current research area in exposure science focuses on improving physicochemical characterization of indoor and outdoor airborne particles, quantification of biological burden and biomarkers of trace elements and metals, and emission source identification using receptor modeling - all of which is essential for human/animal exposure assessment and toxicological/epidemiological studies in multidisciplinary environmental health science research projects. She has been the PI of an NIH R01 project ("Reducing Particulate Matter-Associated Cardiovascular Health Effects for Seniors") since 2014, for which she and her collaborators have been conducting community-based intervention clinical trials focusing on the reduction of both personal exposure to PM2.5 and adverse cardiovascular responses.
She completed her PhD at the University of Michigan (UM) School of Public Health. Prior to joining MSU in 2016, she was Research Associate Professor at the UM, where she directed the Trace Metals Laboratory for the UM Environmental Health Sciences Core Center (funded by NIEHS) and also led various exposure assessment tasks in the Great Lakes Air Center for Integrated Environmental Research (GLACIER, funded by EPA). She now directs the newly-constructed MSU Exposure Science Laboratory and seeks to continue extending her future efforts in community-based environmental health research, focusing on interventions with a particular eye toward tackling environmental health disparity issues.
Publications: Search PubMed at the National Library of Medicine:
Education
Ph.D., School of Public Health, University of Michigan,
Employment
Associate Professor, Michigan State University, East Lansing, -
Publications
Neighborhood air pollution and household environmental health as it relates to respiratory health and healthcare utilization among elderly persons with asthma Journal of Asthma (2020)
Reduced Fine Particulate Matter Air Pollution Exposures Using In-Home Portable Air Cleaners: PILOT RESULTS OF THE CARDIAC REHABILITATION AIR FILTER TRIAL (CRAFT) Journal of cardiopulmonary rehabilitation and prevention (2020)
Serum-borne factors alter cerebrovascular endothelial microRNA expression following particulate matter exposure near an abandoned uranium mine on the Navajo Nation Particle and fibre toxicology (2020)
Acute Blood Pressure and Cardiovascular Effects of Near-Roadway Exposures with and Without N95 Respirators American Journal of Hypertension (2019)
Limitations in the Methodology Assessing Blood Pressure and the Need for Strict Exclusion Criteria - Reply JAMA Internal Medicine (2019)
Reduction of personal PM
Effect of Ambient Fine Particulate Matter Air Pollution and Colder Outdoor Temperatures on High-Density Lipoprotein Function American Journal of Cardiology (2018)
Effect of Portable Air Filtration Systems on Personal Exposure to Fine Particulate Matter and Blood Pressure among Residents in a Low-Income Senior Facility: A Randomized Clinical Trial JAMA Internal Medicine (2018)
Short-term blood pressure responses to ambient fine particulate matter exposures at the extremes of global air pollution concentrations American Journal of Hypertension (2018)
Combustion synthesis of CeO
Personal-level exposure to environmental temperature is a superior predictor of endothelial-dependent vasodilatation than outdoor-ambient level Journal of the American Society of Hypertension (2017)
Acute increase in blood pressure during inhalation of coarse particulate matter air pollution from an urban location Journal of the American Society of Hypertension (2016)
Effects of particle size and coating on toxicologic parameters, fecal elimination kinetics and tissue distribution of acutely ingested silver nanoparticles in a mouse model Nanotoxicology (2016)
In vivo biodistribution and physiologically based pharmacokinetic modeling of inhaled fresh and aged cerium oxide nanoparticles in rats Particle and Fibre Toxicology (2016)
Repeated dose (28-day) administration of silver nanoparticles of varied size and coating does not significantly alter the indigenous murine gut microbiome Nanotoxicology (2016)
Exploration of the composition and sources of urban fine particulate matter associated with same-day cardiovascular health effects in Dearborn, Michigan Journal of Exposure Science and Environmental Epidemiology (2015)
Exposure to concentrated ambient particulate matter induces reversible increase of heart weight in spontaneously hypertensive rats Particle and Fibre Toxicology (2015)
Higher fine particulate matter and temperature levels impair exercise capacity in cardiac patients Heart (2015)
Oil sands development and its impact on atmospheric wet deposition of air pollutants to the Athabasca Oil Sands Region, Alberta, Canada Environmental Pollution (2015)
Particulate matter air pollution and ambient temperature: Opposing effects on blood pressure in high-risk cardiac patients Journal of Hypertension (2015)
The characteristics of coarse particulate matter air pollution associated with alterations in blood pressure and heart rate during controlled exposures Journal of Exposure Science and Environmental Epidemiology (2015)
Trace elements and major ions in atmospheric wet and dry deposition across central Illinois, USA Air Quality, Atmosphere and Health (2015)
Understanding Air Pollution and Cardiovascular Diseases: Is It Preventable? Current Cardiovascular Risk Reports (2015)
Air pollution-mediated susceptibility to inflammation and insulin resistance: Influence of CCR2 pathways in mice Environmental Health Perspectives (2014)
Cardiovascular depression in rats exposed to inhaled particulate matter and ozone: Effects of diet-induced metabolic syndrome Environmental Health Perspectives (2014)
Central IKKβ inhibition prevents air pollution mediated peripheral inflammation and exaggeration of type II diabetes Particle and Fibre Toxicology (2014)
Exaggerated effects of particulate matter air pollution in genetic type II diabetes mellitus Particle and Fibre Toxicology (2014)
Hemodynamic, autonomic, and vascular effects of exposure to coarse particulate matter air pollution from a rural location Environmental Health Perspectives (2014)
Long-term exposure to concentrated ambient PM
No effect of acute exposure to coarse particulate matter air pollution in a rural location on high-density lipoprotein function Inhalation Toxicology (2014)
PM2.5-induced cardiovascular dysregulation in rats is associated with elemental carbon and temperature-resolved carbon subfractions Particle and Fibre Toxicology (2014)
Spatial patterns in wet and dry deposition of atmospheric mercury and trace elements in central Illinois, USA Environmental Science and Pollution Research (2014)
Ambient fine particulate matter and ozone exposures induce inflammation in epicardial and perirenal adipose tissues in rats fed a high fructose diet Particle and Fibre Toxicology (2013)
Assessing the emission sources of atmospheric mercury in wet deposition Across Illinois, USA E3S Web of Conferences (2013)
Assessing the emission sources of atmospheric mercury in wet deposition across Illinois Science of the Total Environment (2013)
Assessing the sources of atmospheric mercury wet deposited in Florida, USA E3S Web of Conferences (2013)
Differential effects of inhalation exposure to PM
Reduced metabolic insulin sensitivity following sub-acute exposures to low levels of ambient fine particulate matter air pollution Science of the Total Environment (2013)
The effect of acute exposure to coarse particulate matter air pollution in a rural location on circulating endothelial progenitor cells: Results from a randomized controlled study Inhalation Toxicology (2013)
Divergent effects of urban particulate air pollution on allergic airway responses in experimental asthma: A comparison of field exposure studies Environmental Health: A Global Access Science Source (2012)
Altered heart rate variability in spontaneously hypertensive rats is associated with specific particulate matter components in Detroit, Michigan Environmental Health Perspectives (2011)
Identification of ambient PM
PM2.5-induced changes in cardiac function of hypertensive rats depend on wind direction and specific sources in Steubenville, Ohio Inhalation Toxicology (2011)
Source identification of ambient PM
Cardiopulmonary responses in spontaneously hypertensive and Wistar-Kyoto rats exposed to concentrated ambient particles from Detroit, Michigan Inhalation Toxicology (2010)
Comparative microarray analysis and pulmonary changes in brown norway rats exposed to ovalbumin and concentrated air particulates Toxicological Sciences (2009)
Effects of concentrated ambient particles and diesel engine exhaust on allergic airway disease in Brown Norway rats. Research report (Health Effects Institute) (2009)
Insights into the mechanisms and mediators of the effects of air pollution exposure on blood pressure and vascular function in healthy humans Hypertension (2009)
Source-to-receptor pathways of anthropogenic PM
Characterization of Urban Atmospheres during Inhalation Exposure Studies in Detroit and Grand Rapids, Michigan Toxicologic Pathology (2007)
Source identification of ambient PM
Characterization of complex mixtures in urban atmospheres for inhalation exposure studies Experimental and Toxicologic Pathology (2005)
Effects of concentrated ambient particles on normal and hypersecretory airways in rats. Research report (Health Effects Institute) (2004)
Effects of concentrated fine ambient particles on rat plasma levels of asymmetric dimethylarginine Inhalation Toxicology (2004)
Pulmonary retention of particulate matter is associated with airway inflammation in allergic rats exposed to air pollution in urban Detroit Inhalation Toxicology (2004)
Assessment of personal and community-level exposures to particulate matter among children with asthma in Detroit, Michigan, as part of Community Action Against Asthma (CAAA) Environmental Health Perspectives (2002)
Evaluating porous-layer open-tubular capillaries as vapor preconcentrators in a microanalytical system Sensors and Actuators, B: Chemical (2000)
Field comparison of PM
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2020 CHM FACULTY AWARDS
Congratulations to Department of Family Medicine's Jennifer M. Edwards-Johnson, DO, Laura M. Santoro, MD, MPH, Masako Morishita, PhD, and Judith E. Arnetz, PhD, on their 2020 Faculty Awards!
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